Semi-automatic COVID-19 vaccine preparation for upscaling of vaccination: a descriptive study

نویسندگان

چکیده

Abstract Objectives Vaccines are used on a large scale for prevention of disease. Preparing vaccines administration can be time consuming process. To increase efficacy vaccine administration, the Vaxtractor was designed in January 2021. With Vaxtractor, desired volume is drawn up automatically syringes from two vials simultaneously. We examined quality COVID-19 prepared with Vaxtractor. Methods Sterility tests and uniformity dosage units were performed. For sterility test, 22 filled 0.5 mL Tryptic Soy Broth these incubated at 25 °C seven days followed by 30 °C. unit difference between empty syringe to compute injectable volume. A analysis performed manually semi-automatically vaccines. Results The showed no signs growth micro-organisms. After optimizing none Comirnaty ® deviated more than 10 % Spikevax 5 compared mean mass acceptance value both below 4 (requirement <15). faster Conclusions safely prepare Further studies should explore applicability preparation other If applicable, this will contribute effective upscaling vaccination programs.

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ژورنال

عنوان ژورنال: Pharmaceutical technology in hospital pharmacy

سال: 2023

ISSN: ['2365-242X', '2365-2411']

DOI: https://doi.org/10.1515/pthp-2023-0005